Sam Cullen is a Deputy Director of the FBI and consequently, Seeley Booth's boss. He does his best to keep Agent Booth on track and frequently disapproves of Dr. Brennan's involvement in FBI field investigations. Not much is known about him, except that he as a teenage daughter named Amy. After a snowboarding accident, Amy received a bone graft that turned out to be from an eldery man who died of a rare form of lung cancer (Mesothelioma). Amy was hospitalized after contracting the cancer, and became friends with forensic artist Angela Montenegro (The Graft in the Girl).

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